What term used to describe combination of transamination and action of glutamate dehydrogenase
Transdeamination
What coenzyme is used with Alanine Aminotransferase
ALT (and all aminotransferases) require the coenzyme pyridoxal phosphate , which is converted into pyridoxamine in the first phase of the reaction, when an amin
What is the name of this functional group?
Schiff Base (Imine)
How is ammonium safely transported in the blood?
Ammonium is safely carried through the blood as glutamine. Glutamine carries 2 NH3's
In what form do humans excrete nitrogen waste from amino acid metabolism
Humans excrete the nitrogenous waste from amino acids as urea
Where does oxidative deamination take place?
In human body deamination takes place primarily in the liver mitochondria - secondarily in kidney
What enzyme is used to convert glutamate to glutamine in the tissues for transport to liver?
Glutamine synthetase
How can one convert alanine to aspartic acid?
Alanine==> Pyruvate ==>Oxaloacetate==>Aspartate
How does ammonia get transferred from skeletal muscles to the liver?
Via the Alanine Cycle - as alanine
Where does transamination take place?
All cells in the body.
What is the name of the enzyme that catalyzes the deamination of glutamine?
Glutaminase
What enzyme can use both NAD+ and NADP+?
Glutamate dehydrogenase
What is the name of the coenzyme involved in transaminase reactions
Pyridoxal phosphate is a coenzyme associated with — transaminases which catalyze transfer of amino groups from amino acids to keto acids.
What enzyme is used in the muscle to transfer NH3 from Glu to Ala?
Alanine aminotransferase (ALT)
What three amino acids can be made from a single non-amino acid by transamination