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Higher Biology - Unit 1

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  • The genetic material in human mitochondria is arranged as:
    Linear chromosomes
    Circular chromosomes
    Linear plasmids
    Circular plasmids
  • Which of the following are required in a polymerase chain reaction (PCR)?
    RNA polymerase, template strand and primers
    RNA polymerase, ligase and primers
    DNA polymerase, template strand and ligase
    DNA polymerase, template strand and primers
  • Normal DNA - ATTTTTTACG. Mutated DNA - ATTTATTTACG. Which type of mutation has occurred?
    Insertion
    Deletion
    Substitution
    Inversion
  • Natural selection of human babies of medium rather than low or high mass is an example of?
    Disruptive selection
    Directional selection
    Sexual selection
    Stabilising selection
  • Which type of mutation would affect only one amino acid in the polypeptide produced?
    Deletion
    All of the above
    Substitution
    Insertion
  • During PCR, which of the following occurs at the highest temperature?
    Primers bind
    DNA polymerase adds nucleotides
    Strands separated
    Ligase joins DNA fragments
  • What word describes the process by which a cell develops more specialised functions?
    Replication
    Translation
    Transcription
    Differentiation
  • How much of the genome is made up of regions that code for DNA?
    Around 50%
    All of it
    Around 95%
    Around 2%
  • The insertion of an extra nucleotide into a DNA sequence results in what?
    Frameshift mutation
    Nonsense mutation
    Neutral mutation
    Missense mutation
  • If a protein contains 120 amino acids then how many bases were present in the original gene?
    360
    40
    120
    60
  • The main components of a ribosome are:
    mRNA and rRNA
    mRNA and protein
    rRNA and protein
    mRNA and tRNA
  • PCR is a technique used for what?
    The amplification of DNA in vitro
    The amplification of DNA in vivo
    The amplification of DNA in limbo
    The amplification of DNA in livin la vida loca
  • Which of the following is a potential downside to stem cell research?
    They can be used as model cells
    There are ethical issues surrounding their use
    They can be used to repair damaged or diseased organs
    They can be used to investigate how cells become specialised
  • Which type of RNA carries a copy of the genetic code from the nucleus to the ribosome?
    tRNA
    rRNA
    zRNA
    mRNA
  • Which of the following is true of RNA?
    Possesses the base uracil
    Contains deoxyribose
    Is made up of 2 strands
    All of the above
  • The process of editing a primary transcript to produce a mature RNA transcript is called what?
    Translation
    RNA splicing
    Transcription
    Modification
  • What parts are removed from the primary transcript when producing the mature RNA transcript?
    Bases
    Exons
    Introns
    Coding regions
  • What kind of cells are found in animals and produce specialised cells of one or more types?
    Haploid
    Meristems
    Differentiation cells
    Stem cells
  • Normal DNA - ATCCCCCTACC. Mutated DNA - ATCCACCTACC. Which type of mutation has occurred?
    Insertion
    Inversion
    Deletion
    Substitution
  • Fragments of DNA which have been replicated discontinuously are joined together using what?
    Protease
    Ligase
    Restriction endonuclease
    DNA polymerase
  • Which of the following is true of meristems?
    Unspecialised animal cells
    Unspecialised plant cells
    Specialised plant cells
    Specialised animal cells
  • 1000 DNA fragments are present at the start of a 5 min PCR cycle. How many after 20 min?
    32000
    16000
    4000
    8000
  • What are DNA nucleotides made up of?
    A deoxyribose sugar, phosphate and base
    A ribose sugar, phosphate and base
    A deoxyribose sugar, phosphate and ATP
    A ribose sugar, phosphate and ATP
  • When part of a chromosome becomes attached to another chromosome it is known as what?
    Translocation
    Duplication
    Inversion
    Deletion
  • Which type of natural selection can lead to speciation?
    Stabilising
    Directional
    Disruptive
    Dimensional
  • What are the DNA base pairing rules?
    Adenine to Thymine, Cytosine to Guanine
    Adenine to Guanine, Cytosine to Thymine
    Adenine to Cytosine, Thymine to Guanine
    Adenine to Uracil, Cytosine to Guanine
  • Which of the following is NOT one of the three domains of life?
    Archaea
    Eukaryotes
    Prokaryotes
    Bacteria
  • What kind of bonds form between adjacent amino acids in protein synthesis at the ribosome?
    Peptide
    Strong chemical
    Disulphide bridges
    Hydrogen
  • Substitution, insertion or deletion of a single nucleotide in a DNA sequence is known as:
    Translocation mutation
    Polyploidy
    Chromosome structure mutation
    Single gene mutation
  • The two strands of DNA are held together by which kind of bonds?
    Strong chemical
    Peptide
    Phosphate
    Hydrogen
  • What stage of protein synthesis occurs in the nucleus?
    Cutting and combining
    Formation of the final 3D protein shape
    Translation
    Transcription
  • Which of the following is the correct order of evolution?
    prokaryotes > cells > eukaryotes > animals > land plants
    cells > prokaryotes > eukaryotes > land plants > animals
    cells > prokaryotes > animals > eukaryotes > land plants
    cells > prokaryotes > eukaryotes > animals > land plants
  • Which type of chromosome structure mutation is important for evolution?
    Inversion
    Translocation
    Duplication
    Deletion
  • Which of the following barriers would not be involved in an example of sympatric speciation?
    Behavioural
    Geographical
    Ecological
  • Which of the following are involved in transcription of DNA but not replication of DNA?
    Primers
    RNA polymerase
    Ligase
    DNA polymerase
  • Why can both strands of DNA not be replicated continuously?
    DNA nucleotides can only be added in a 5’ to 3’ direction
    DNA nucleotides can only be added in a 3’ to 5’ direction
    There is not enough space for both strands to be copied
    The DNA polymerase can only act on one strand at a time
  • What is the name for the basic units which make up strands of DNA?
    Bases
    Sugars
    Nucleotides
    Phosphates
  • The study of evolutionary relatedness is known as what?
    Bioinformatics
    Pharmacogenetics
    Phylogenetics
    Speciation
  • Which of these enzymes is required for DNA replication?
    Ligase
    Restriction endonuclease
    Amylase
    Dehydrogenase
  • Name the trio who won the 1962 Nobel Prize in Medicine for their discovery of DNA's structure.
    Watson, Crick and Wilkins
    Rowland, Knowles and Williams
    Diamond, Yauch and Horowitz
    Best, Law and Charlton