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Higher Biology - Unit 1
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The genetic material in human mitochondria is arranged as:
Linear chromosomes
Circular chromosomes
Linear plasmids
Circular plasmids
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Which of the following are required in a polymerase chain reaction (PCR)?
RNA polymerase, template strand and primers
RNA polymerase, ligase and primers
DNA polymerase, template strand and ligase
DNA polymerase, template strand and primers
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Normal DNA - ATTTTTTACG. Mutated DNA - ATTTATTTACG. Which type of mutation has occurred?
Insertion
Deletion
Substitution
Inversion
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Natural selection of human babies of medium rather than low or high mass is an example of?
Disruptive selection
Directional selection
Sexual selection
Stabilising selection
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Which type of mutation would affect only one amino acid in the polypeptide produced?
Deletion
All of the above
Substitution
Insertion
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During PCR, which of the following occurs at the highest temperature?
Primers bind
DNA polymerase adds nucleotides
Strands separated
Ligase joins DNA fragments
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What word describes the process by which a cell develops more specialised functions?
Replication
Translation
Transcription
Differentiation
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How much of the genome is made up of regions that code for DNA?
Around 50%
All of it
Around 95%
Around 2%
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The insertion of an extra nucleotide into a DNA sequence results in what?
Frameshift mutation
Nonsense mutation
Neutral mutation
Missense mutation
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If a protein contains 120 amino acids then how many bases were present in the original gene?
360
40
120
60
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The main components of a ribosome are:
mRNA and rRNA
mRNA and protein
rRNA and protein
mRNA and tRNA
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PCR is a technique used for what?
The amplification of DNA in vitro
The amplification of DNA in vivo
The amplification of DNA in limbo
The amplification of DNA in livin la vida loca
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Which of the following is a potential downside to stem cell research?
They can be used as model cells
There are ethical issues surrounding their use
They can be used to repair damaged or diseased organs
They can be used to investigate how cells become specialised
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Which type of RNA carries a copy of the genetic code from the nucleus to the ribosome?
tRNA
rRNA
zRNA
mRNA
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Which of the following is true of RNA?
Possesses the base uracil
Contains deoxyribose
Is made up of 2 strands
All of the above
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The process of editing a primary transcript to produce a mature RNA transcript is called what?
Translation
RNA splicing
Transcription
Modification
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What parts are removed from the primary transcript when producing the mature RNA transcript?
Bases
Exons
Introns
Coding regions
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What kind of cells are found in animals and produce specialised cells of one or more types?
Haploid
Meristems
Differentiation cells
Stem cells
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Normal DNA - ATCCCCCTACC. Mutated DNA - ATCCACCTACC. Which type of mutation has occurred?
Insertion
Inversion
Deletion
Substitution
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Fragments of DNA which have been replicated discontinuously are joined together using what?
Protease
Ligase
Restriction endonuclease
DNA polymerase
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Which of the following is true of meristems?
Unspecialised animal cells
Unspecialised plant cells
Specialised plant cells
Specialised animal cells
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1000 DNA fragments are present at the start of a 5 min PCR cycle. How many after 20 min?
32000
16000
4000
8000
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What are DNA nucleotides made up of?
A deoxyribose sugar, phosphate and base
A ribose sugar, phosphate and base
A deoxyribose sugar, phosphate and ATP
A ribose sugar, phosphate and ATP
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When part of a chromosome becomes attached to another chromosome it is known as what?
Translocation
Duplication
Inversion
Deletion
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Which type of natural selection can lead to speciation?
Stabilising
Directional
Disruptive
Dimensional
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What are the DNA base pairing rules?
Adenine to Thymine, Cytosine to Guanine
Adenine to Guanine, Cytosine to Thymine
Adenine to Cytosine, Thymine to Guanine
Adenine to Uracil, Cytosine to Guanine
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Which of the following is NOT one of the three domains of life?
Archaea
Eukaryotes
Prokaryotes
Bacteria
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What kind of bonds form between adjacent amino acids in protein synthesis at the ribosome?
Peptide
Strong chemical
Disulphide bridges
Hydrogen
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Substitution, insertion or deletion of a single nucleotide in a DNA sequence is known as:
Translocation mutation
Polyploidy
Chromosome structure mutation
Single gene mutation
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The two strands of DNA are held together by which kind of bonds?
Strong chemical
Peptide
Phosphate
Hydrogen
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What stage of protein synthesis occurs in the nucleus?
Cutting and combining
Formation of the final 3D protein shape
Translation
Transcription
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Which of the following is the correct order of evolution?
prokaryotes > cells > eukaryotes > animals > land plants
cells > prokaryotes > eukaryotes > land plants > animals
cells > prokaryotes > animals > eukaryotes > land plants
cells > prokaryotes > eukaryotes > animals > land plants
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Which type of chromosome structure mutation is important for evolution?
Inversion
Translocation
Duplication
Deletion
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Which of the following barriers would not be involved in an example of sympatric speciation?
Behavioural
Geographical
Ecological
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Which of the following are involved in transcription of DNA but not replication of DNA?
Primers
RNA polymerase
Ligase
DNA polymerase
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Why can both strands of DNA not be replicated continuously?
DNA nucleotides can only be added in a 5’ to 3’ direction
DNA nucleotides can only be added in a 3’ to 5’ direction
There is not enough space for both strands to be copied
The DNA polymerase can only act on one strand at a time
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What is the name for the basic units which make up strands of DNA?
Bases
Sugars
Nucleotides
Phosphates
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The study of evolutionary relatedness is known as what?
Bioinformatics
Pharmacogenetics
Phylogenetics
Speciation
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Which of these enzymes is required for DNA replication?
Ligase
Restriction endonuclease
Amylase
Dehydrogenase
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Name the trio who won the 1962 Nobel Prize in Medicine for their discovery of DNA's structure.
Watson, Crick and Wilkins
Rowland, Knowles and Williams
Diamond, Yauch and Horowitz
Best, Law and Charlton
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