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Higher Biology - Unit 1
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The two strands of DNA are held together by which kind of bonds?
Peptide
Strong chemical
Hydrogen
Phosphate
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The genetic material in human mitochondria is arranged as:
Circular plasmids
Circular chromosomes
Linear plasmids
Linear chromosomes
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Which type of RNA carries a copy of the genetic code from the nucleus to the ribosome?
tRNA
mRNA
zRNA
rRNA
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Which type of chromosome structure mutation is important for evolution?
Deletion
Duplication
Translocation
Inversion
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What parts are removed from the primary transcript when producing the mature RNA transcript?
Exons
Bases
Coding regions
Introns
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PCR is a technique used for what?
The amplification of DNA in limbo
The amplification of DNA in vivo
The amplification of DNA in livin la vida loca
The amplification of DNA in vitro
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The study of evolutionary relatedness is known as what?
Speciation
Phylogenetics
Bioinformatics
Pharmacogenetics
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The insertion of an extra nucleotide into a DNA sequence results in what?
Missense mutation
Neutral mutation
Frameshift mutation
Nonsense mutation
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Which type of natural selection can lead to speciation?
Dimensional
Disruptive
Stabilising
Directional
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Name the trio who won the 1962 Nobel Prize in Medicine for their discovery of DNA's structure.
Diamond, Yauch and Horowitz
Watson, Crick and Wilkins
Rowland, Knowles and Williams
Best, Law and Charlton
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What are DNA nucleotides made up of?
A deoxyribose sugar, phosphate and base
A ribose sugar, phosphate and base
A ribose sugar, phosphate and ATP
A deoxyribose sugar, phosphate and ATP
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Normal DNA - ATTTTTTACG. Mutated DNA - ATTTATTTACG. Which type of mutation has occurred?
Insertion
Inversion
Deletion
Substitution
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When part of a chromosome becomes attached to another chromosome it is known as what?
Translocation
Inversion
Deletion
Duplication
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Natural selection of human babies of medium rather than low or high mass is an example of?
Stabilising selection
Disruptive selection
Sexual selection
Directional selection
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What word describes the process by which a cell develops more specialised functions?
Transcription
Replication
Differentiation
Translation
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During PCR, which of the following occurs at the highest temperature?
Ligase joins DNA fragments
Primers bind
Strands separated
DNA polymerase adds nucleotides
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The process of editing a primary transcript to produce a mature RNA transcript is called what?
Transcription
Modification
RNA splicing
Translation
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How much of the genome is made up of regions that code for DNA?
Around 2%
Around 50%
Around 95%
All of it
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Which of the following barriers would not be involved in an example of sympatric speciation?
Ecological
Geographical
Behavioural
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Which of the following is the correct order of evolution?
cells > prokaryotes > eukaryotes > land plants > animals
cells > prokaryotes > eukaryotes > animals > land plants
cells > prokaryotes > animals > eukaryotes > land plants
prokaryotes > cells > eukaryotes > animals > land plants
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Which type of mutation would affect only one amino acid in the polypeptide produced?
Insertion
All of the above
Substitution
Deletion
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Which of the following are involved in transcription of DNA but not replication of DNA?
DNA polymerase
RNA polymerase
Primers
Ligase
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Substitution, insertion or deletion of a single nucleotide in a DNA sequence is known as:
Polyploidy
Chromosome structure mutation
Translocation mutation
Single gene mutation
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Which of the following is a potential downside to stem cell research?
They can be used to investigate how cells become specialised
They can be used to repair damaged or diseased organs
They can be used as model cells
There are ethical issues surrounding their use
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Which of the following are required in a polymerase chain reaction (PCR)?
DNA polymerase, template strand and primers
RNA polymerase, ligase and primers
RNA polymerase, template strand and primers
DNA polymerase, template strand and ligase
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Which of the following is NOT one of the three domains of life?
Eukaryotes
Prokaryotes
Bacteria
Archaea
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Which of the following is true of meristems?
Specialised plant cells
Unspecialised plant cells
Unspecialised animal cells
Specialised animal cells
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What are the DNA base pairing rules?
Adenine to Uracil, Cytosine to Guanine
Adenine to Thymine, Cytosine to Guanine
Adenine to Guanine, Cytosine to Thymine
Adenine to Cytosine, Thymine to Guanine
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What stage of protein synthesis occurs in the nucleus?
Transcription
Cutting and combining
Formation of the final 3D protein shape
Translation
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Why can both strands of DNA not be replicated continuously?
DNA nucleotides can only be added in a 3’ to 5’ direction
The DNA polymerase can only act on one strand at a time
DNA nucleotides can only be added in a 5’ to 3’ direction
There is not enough space for both strands to be copied
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What is the name for the basic units which make up strands of DNA?
Phosphates
Nucleotides
Sugars
Bases
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What kind of bonds form between adjacent amino acids in protein synthesis at the ribosome?
Peptide
Strong chemical
Disulphide bridges
Hydrogen
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1000 DNA fragments are present at the start of a 5 min PCR cycle. How many after 20 min?
4000
16000
32000
8000
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What kind of cells are found in animals and produce specialised cells of one or more types?
Differentiation cells
Stem cells
Haploid
Meristems
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Normal DNA - ATCCCCCTACC. Mutated DNA - ATCCACCTACC. Which type of mutation has occurred?
Inversion
Deletion
Insertion
Substitution
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If a protein contains 120 amino acids then how many bases were present in the original gene?
60
360
40
120
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Fragments of DNA which have been replicated discontinuously are joined together using what?
DNA polymerase
Ligase
Restriction endonuclease
Protease
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Which of these enzymes is required for DNA replication?
Ligase
Amylase
Restriction endonuclease
Dehydrogenase
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Which of the following is true of RNA?
Possesses the base uracil
Contains deoxyribose
All of the above
Is made up of 2 strands
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The main components of a ribosome are:
mRNA and protein
rRNA and protein
mRNA and tRNA
mRNA and rRNA
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Okay!
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