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Higher Biology - Unit 1

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  • The two strands of DNA are held together by which kind of bonds?
    Peptide
    Strong chemical
    Hydrogen
    Phosphate
  • The genetic material in human mitochondria is arranged as:
    Circular plasmids
    Circular chromosomes
    Linear plasmids
    Linear chromosomes
  • Which type of RNA carries a copy of the genetic code from the nucleus to the ribosome?
    tRNA
    mRNA
    zRNA
    rRNA
  • Which type of chromosome structure mutation is important for evolution?
    Deletion
    Duplication
    Translocation
    Inversion
  • What parts are removed from the primary transcript when producing the mature RNA transcript?
    Exons
    Bases
    Coding regions
    Introns
  • PCR is a technique used for what?
    The amplification of DNA in limbo
    The amplification of DNA in vivo
    The amplification of DNA in livin la vida loca
    The amplification of DNA in vitro
  • The study of evolutionary relatedness is known as what?
    Speciation
    Phylogenetics
    Bioinformatics
    Pharmacogenetics
  • The insertion of an extra nucleotide into a DNA sequence results in what?
    Missense mutation
    Neutral mutation
    Frameshift mutation
    Nonsense mutation
  • Which type of natural selection can lead to speciation?
    Dimensional
    Disruptive
    Stabilising
    Directional
  • Name the trio who won the 1962 Nobel Prize in Medicine for their discovery of DNA's structure.
    Diamond, Yauch and Horowitz
    Watson, Crick and Wilkins
    Rowland, Knowles and Williams
    Best, Law and Charlton
  • What are DNA nucleotides made up of?
    A deoxyribose sugar, phosphate and base
    A ribose sugar, phosphate and base
    A ribose sugar, phosphate and ATP
    A deoxyribose sugar, phosphate and ATP
  • Normal DNA - ATTTTTTACG. Mutated DNA - ATTTATTTACG. Which type of mutation has occurred?
    Insertion
    Inversion
    Deletion
    Substitution
  • When part of a chromosome becomes attached to another chromosome it is known as what?
    Translocation
    Inversion
    Deletion
    Duplication
  • Natural selection of human babies of medium rather than low or high mass is an example of?
    Stabilising selection
    Disruptive selection
    Sexual selection
    Directional selection
  • What word describes the process by which a cell develops more specialised functions?
    Transcription
    Replication
    Differentiation
    Translation
  • During PCR, which of the following occurs at the highest temperature?
    Ligase joins DNA fragments
    Primers bind
    Strands separated
    DNA polymerase adds nucleotides
  • The process of editing a primary transcript to produce a mature RNA transcript is called what?
    Transcription
    Modification
    RNA splicing
    Translation
  • How much of the genome is made up of regions that code for DNA?
    Around 2%
    Around 50%
    Around 95%
    All of it
  • Which of the following barriers would not be involved in an example of sympatric speciation?
    Ecological
    Geographical
    Behavioural
  • Which of the following is the correct order of evolution?
    cells > prokaryotes > eukaryotes > land plants > animals
    cells > prokaryotes > eukaryotes > animals > land plants
    cells > prokaryotes > animals > eukaryotes > land plants
    prokaryotes > cells > eukaryotes > animals > land plants
  • Which type of mutation would affect only one amino acid in the polypeptide produced?
    Insertion
    All of the above
    Substitution
    Deletion
  • Which of the following are involved in transcription of DNA but not replication of DNA?
    DNA polymerase
    RNA polymerase
    Primers
    Ligase
  • Substitution, insertion or deletion of a single nucleotide in a DNA sequence is known as:
    Polyploidy
    Chromosome structure mutation
    Translocation mutation
    Single gene mutation
  • Which of the following is a potential downside to stem cell research?
    They can be used to investigate how cells become specialised
    They can be used to repair damaged or diseased organs
    They can be used as model cells
    There are ethical issues surrounding their use
  • Which of the following are required in a polymerase chain reaction (PCR)?
    DNA polymerase, template strand and primers
    RNA polymerase, ligase and primers
    RNA polymerase, template strand and primers
    DNA polymerase, template strand and ligase
  • Which of the following is NOT one of the three domains of life?
    Eukaryotes
    Prokaryotes
    Bacteria
    Archaea
  • Which of the following is true of meristems?
    Specialised plant cells
    Unspecialised plant cells
    Unspecialised animal cells
    Specialised animal cells
  • What are the DNA base pairing rules?
    Adenine to Uracil, Cytosine to Guanine
    Adenine to Thymine, Cytosine to Guanine
    Adenine to Guanine, Cytosine to Thymine
    Adenine to Cytosine, Thymine to Guanine
  • What stage of protein synthesis occurs in the nucleus?
    Transcription
    Cutting and combining
    Formation of the final 3D protein shape
    Translation
  • Why can both strands of DNA not be replicated continuously?
    DNA nucleotides can only be added in a 3’ to 5’ direction
    The DNA polymerase can only act on one strand at a time
    DNA nucleotides can only be added in a 5’ to 3’ direction
    There is not enough space for both strands to be copied
  • What is the name for the basic units which make up strands of DNA?
    Phosphates
    Nucleotides
    Sugars
    Bases
  • What kind of bonds form between adjacent amino acids in protein synthesis at the ribosome?
    Peptide
    Strong chemical
    Disulphide bridges
    Hydrogen
  • 1000 DNA fragments are present at the start of a 5 min PCR cycle. How many after 20 min?
    4000
    16000
    32000
    8000
  • What kind of cells are found in animals and produce specialised cells of one or more types?
    Differentiation cells
    Stem cells
    Haploid
    Meristems
  • Normal DNA - ATCCCCCTACC. Mutated DNA - ATCCACCTACC. Which type of mutation has occurred?
    Inversion
    Deletion
    Insertion
    Substitution
  • If a protein contains 120 amino acids then how many bases were present in the original gene?
    60
    360
    40
    120
  • Fragments of DNA which have been replicated discontinuously are joined together using what?
    DNA polymerase
    Ligase
    Restriction endonuclease
    Protease
  • Which of these enzymes is required for DNA replication?
    Ligase
    Amylase
    Restriction endonuclease
    Dehydrogenase
  • Which of the following is true of RNA?
    Possesses the base uracil
    Contains deoxyribose
    All of the above
    Is made up of 2 strands
  • The main components of a ribosome are:
    mRNA and protein
    rRNA and protein
    mRNA and tRNA
    mRNA and rRNA