Study

Infections in pregnancy

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  • sexually transmitted infections from this module (3)
    HIV, zika, CMV
  • symptomas of varicella pneumonia
    develops 2-5 days after onset of rash (sx: cough, dyspnea, pleurisy, and hemoptysis)
  • Spiramycin is treatment for which infection: A. Varicella B. Listeriosis C. Toxoplasmosis D. CMV
    C.
  • Transmitted in breastmilk (2) - there are more, but these two are the mayor guys.
    HIV, CMV
  • When would we treat latent TB in pregnant woman?
    If she develops active disease (symptoms) or is immunocompromised (HIV..)
  • maternal risks of TB (2)
    Preeclampsia Hemorrhage
  • Fetal complications of 5th disease/ Parovirus B19
    Fetal anemia - non immune hydrops, heart failure Rare: direct infection of fetal myocardium 11% fetal loss for infections < 20 wks
  • Clinical presentation of varicella syndrome in newborn
    Skin scarring in dermatomal distribution Limb hypoplasia and/or paresis Low birth weight Less common: microcephaly, neurologic deficits, eye defects
  • Who should VZIG be offered to?
    seronegative pregnant woman with a significant contact.
  • Which tests would we run during prenatal care of a HIV positive patient?
    HIV RNA viral load, CD4 count in 1st and 2nd trimester TORCH, STD screen in 1st and 3rd trimester Pap smear twice (eight weeks apart) Watch for PTL
  • How can we detect neonatal HIV infection?
    polymerase chain reaction
  • HIV transmission to baby
    vertical or breastmilk
  • Pt. education on Rifampin (odd fact)
    discolors urine orange
  • Fetal risks of Toxoplasmosis
    chorioretinitis, hydrocephaly or microcephaly, cerebral calcification
  • Fetal risks of TB
    Fetal loss Low birthweight Congenital TB (extremely rare in US)
  • Do all HIV+ women have to deliver by C/S?
    Only if high viral load.
  • Criteria for GBS prophylaxis in current pregnancy
    Previous infant with GBS disease, +GBS bacteriuria or Swab, unknown GBS AND either <37 wks, SROM >18 hrs, temp >100.4F
  • The most common and most easily preventable cause of poor birth outcomes in the world
    Malaria
  • Incubation period for varicella compared to flu.
    2 weeks vs 2-4 days.
  • When would we give VZIG to the newborn?
    If mom develops varicella during last 7 days of pregnancy or the first 14 days after delivery
  • which infection is caused by a parasite? A. Listeriosis B. Rubella C. Hepatitis B D. Toxoplasmosis
    D. Toxoplasmosis
  • clinical presentation and history of listeriosis
    woman with nonspecific flu-like symptoms who ate uncooked lunch meats (or hot dogs, non pasteurized milk products)
  • Treatment of TB in pregnancy
    Isoniazid, Rifampin, Ethambutol
  • Which infection causes severe anemia and thrombocytopenia?
    Malaria
  • explain the mechanism of why someone with malaria has a higher risk of PPH?
    Anemia = less efficient uterine ctx = PP hemorrhage
  • fetal complications of CMV infection (6)
    1. micro-& hydrocephaly 2. chorioretinitis 3. cerebral calcification 4. mental retardation 5. heart block 6. petechiae
  • Patients on Isoniazid should take this supplement to avoid deficiency.
    Vit B6
  • Treatment for varicella pneumonia
    Acyclovir
  • Route of transmission of rubella: A. Droplets B. Feces C. Fomites D. Blood E. Air
    A.
  • fetal risks of Parovirus B19
    Fetal anemia and hydrops
  • Which fetus has the highest risk of congenital rubella syndrome? A. 8 weeks B. 22 weeks C. 36 weeks
    A.
  • Bacterial infections from this module (2)
    Listeriosis, GBS
  • Which infection starts with lymphadenopathy in the postauricular, deep cervical and suboccipital chains?
    Rubella
  • Signs indicating complicated malaria (5)
    Dizziness Breathlessness/difficulty breathing Sleepy/drowsy Confusion/coma Sometimes fits, jaundice, severe dehydration
  • which infections are caused by a parasite? (2)
    Toxoplasmosis, malaria
  • Flu treatment in pregnancy
    A and B: Zanamivir and Oseltamivir (P.Cat. C) Start within 24-36 hrs symptom onset A: Amantidine and Rimantidine (P. Cat. C) Antibiotics to prevent secondary