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Infections in pregnancy

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Fetal risks of Toxoplasmosis

chorioretinitis, hydrocephaly or microcephaly, cerebral calcification

which infections are caused by a parasite? (2)

Toxoplasmosis, malaria

which infection is caused by a parasite? A. Listeriosis B. Rubella C. Hepatitis B D. Toxoplasmosis

D. Toxoplasmosis

Spiramycin is treatment for which infection: A. Varicella B. Listeriosis C. Toxoplasmosis D. CMV

fetal complications of CMV infection (6)

1. micro-& hydrocephaly 2. chorioretinitis 3. cerebral calcification 4. mental retardation 5. heart block 6. petechiae

Who should VZIG be offered to?

seronegative pregnant woman with a significant contact.

Treatment for varicella pneumonia

Acyclovir

symptomas of varicella pneumonia

develops 2-5 days after onset of rash (sx: cough, dyspnea, pleurisy, and hemoptysis)

Clinical presentation of varicella syndrome in newborn

Skin scarring in dermatomal distribution Limb hypoplasia and/or paresis Low birth weight Less common: microcephaly, neurologic deficits, eye defects

When would we give VZIG to the newborn?

If mom develops varicella during last 7 days of pregnancy or the first 14 days after delivery

Which tests would we run during prenatal care of a HIV positive patient?

HIV RNA viral load, CD4 count in 1st and 2nd trimester TORCH, STD screen in 1st and 3rd trimester Pap smear twice (eight weeks apart) Watch for PTL

How can we detect neonatal HIV infection?

polymerase chain reaction

Do all HIV+ women have to deliver by C/S?

Only if high viral load.

HIV transmission to baby

vertical or breastmilk

Flu treatment in pregnancy

A and B: Zanamivir and Oseltamivir (P.Cat. C) Start within 24-36 hrs symptom onset A: Amantidine and Rimantidine (P. Cat. C) Antibiotics to prevent secondary

Fetal complications of 5th disease/ Parovirus B19

Fetal anemia - non immune hydrops, heart failure Rare: direct infection of fetal myocardium 11% fetal loss for infections < 20 wks