Study

Cell Signaling Part 2

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  • What is the total number of subunits present on cAMP dependent protein kinases (PKA)?
    4
  • Binding of ________ α subunit dissociates from trimmer of G protein
    GTP
  • Which protein binds PKA to the cytoskeleton ?
    A kinase anchoring protein (AKAP)
  • Full form of GPCR
    G proteinn coupled receptor
  • Any one ligand for nuclear receptor
    Steroid hormones, Thyroid hormones, Retinoid etc
  • What is the function of loops of GPCR on cytosolic side of plasma membrane?
    Binding site for G protein/Arrestin
  • Give an example of enzyme that brings about phosphorylation
    Kinases
  • How many times polypeptide of GPCR intervene plasma membrane ?
    7
  • What is the function of GTPase-activating proteins?
    (GAPs) drive the proteins into an “off” state by increasing the rate of hydrolysis of bound GTP.
  • Which two sub-units of G protein are linked to plasma membrane?
    α and γ.