Give an example of enzyme that brings about phosphorylation
Kinases
Any one ligand for nuclear receptor
Steroid hormones, Thyroid hormones, Retinoid etc
What is the function of GTPase-activating proteins?
(GAPs) drive the proteins into an “off” state by increasing the rate of hydrolysis of bound GTP.
Full form of GPCR
G proteinn coupled receptor
How many times polypeptide of GPCR intervene plasma membrane ?
7
What is the function of loops of GPCR on cytosolic side of plasma membrane?
Binding site for G protein/Arrestin
Which two sub-units of G protein are linked to plasma membrane?
α and γ.
Binding of ________ α subunit dissociates from trimmer of G protein
GTP
What is the total number of subunits present on cAMP dependent protein kinases (PKA)?
4
Which protein binds PKA to the cytoskeleton ?
A kinase anchoring protein (AKAP)
