Unit 8 drugs | Baamboozle - Baamboozle | The Most Fun Classroom Games!

English 12 Public

Unit 8 drugs

Study Slideshow

Rationalize the use of mannitol in acute TBI

reduce ICP by reducing blood viscosity -> increases cerebral blood flow and oxygen transport and constricts pial arterioles -> reduce cerebral blood volume, ICP

Explain the rationale for the use of fosphenytoin for seizure prophylaxis following TBI

Anticonvulsant - stabilize neuronal membranes & decrease seizure activity by increase efflux/decrease influx Na+ across cell membrane during generation nerve im

Identify the MOA of the six different drug therapies used to manage PD symptoms

COMT inhibitor (Tolcapone)) and MAO-B inhibitor (Selegiline) ->

Identify a physiologic rationale for the declining efficacy of carbidopa-levodopa treatment over time in PD.

What is the MOA of the first-line Alzheimer disease treatment

Donepezil - cholinesterase inhibitor - Boost the amount of ACh in the brain -> higher ACh in synapse, more likely to have a signal -> improve symptoms of dement

What is the MOA of the second-line Alzheimer disease treatment

Memantine - NMDA receptor blocker - decreases effects of glutamate (known to cause neuronal toxicity)

Outline how cannabinoids would alter action potentials to improve MS-related spasticity.

Cannabinoids decrease the release of pre-synaptic glutamate-> decrease the amplitude of EPSPs-> decrease excitability of motor pathway in CNS ->

Justify the use of tPA in ischemic stroke

Alteplase

Justify the use of diuretics in the treatment of Meniere's disease

Theoretically improves symptoms by reducing the endolymph volume but high-quality studies on the effect of diuretics are lacking

Distinguish abortive and preventative pharmacotherapies for migraine headache.

Identify two subclasses of sedative-hypnotics to treat insomnia. Include MOA

What is the first-line treatment for anxiety disorders