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Neuromuscular Junction Disorder EMG

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    Electordiagnosis
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  • This condition is characterized by antibodies against voltage gated Ca++ channels in the NMJ.
    Eaton Lamberg Syndrome
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  • This substance can cause Descending weakness ( CN muscles-> shoulders->feet).
    Botulinum toxin
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  • This condition is caused by deficiency in presynaptic ACH release.
    Botulinum toxin/Eaton- Lambert Myasthenic Syndrome
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  • This condition is caused by deficiency in ACH storage, mobilization, re-synthesis and as muscle weakness in NEWBORN.
    Congenital Myasthenia
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  • In this condition, antibodies block ACH receptors at postsynaptic neuromuscular junction of skeletal muscles
    Myasthenia Gravis
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  • In this condition, ACHesterase inhibitor (Edrophonium) reverses weakness.
    Myasthenia Gravis
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  • This condition of general weakness and fatique is associated with thymoma
    Myasthenia Gravis
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  • In this phenomenon, increased CMAP amplitudes are seen with repetitive stimulation (after subsequent stimulation) due to better SYNCHRONY of muscle fibers action potentials.
    Pseudofacilitation
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  • What % is considered significant?
    10% decrement
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  • This phenomenon occurs after high rates of stimulation (20-50HZ) or tetanic contraction
    Post-tetanic facilitation or potentiation
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  • Which NMJ condition is associated with small cell lung cancer
    Eaton-Lamberg Syndrome
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  • Which NMJ is associated with dry mouth, metallic taste, constipation, erectile dysfunction?
    Eaton-Lamberg Syndrome
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  • Which NMJ disorder usually spares bulbar and extraoccular muscles?
    Eaton-Lamberg Syndrome
  •  15
  • Which NMJ condition is associated with reduced MEPP amplitudes?
    Myasthenia Gravis
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  • Which NMJ condition is associated with very low CMAP amplitude on NCS?
    Eaton-Lamberg Myasthenic syndrome
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  • This term is defined as the VARIABILITY of potential time between 2 action potentials from 2 muscle fibers belonging to the same unit.
    Jitter
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