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Neuromuscular Junction Disorder EMG
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This terminology describes the phenomenon when there is so much jitter that the second potential doesn't show up.
Blocking
This term is defined as the VARIABILITY of potential time between 2 action potentials from 2 muscle fibers belonging to the same unit.
Jitter
Which NMJ condition is associated with very low CMAP amplitude on NCS?
Eaton-Lamberg Myasthenic syndrome
Which NMJ condition is associated with reduced MEPP amplitudes?
Myasthenia Gravis
Which NMJ disorder usually spares bulbar and extraoccular muscles?
Eaton-Lamberg Syndrome
Which NMJ is associated with dry mouth, metallic taste, constipation, erectile dysfunction?
Eaton-Lamberg Syndrome
Which NMJ condition is associated with small cell lung cancer
Eaton-Lamberg Syndrome
This phenomenon occurs after high rates of stimulation (20-50HZ) or tetanic contraction
Post-tetanic facilitation or potentiation
What % is considered significant?
10% decrement
In this phenomenon, increased CMAP amplitudes are seen with repetitive stimulation (after subsequent stimulation) due to better SYNCHRONY of muscle fibers action potentials.
Pseudofacilitation
This condition of general weakness and fatique is associated with thymoma
Myasthenia Gravis
In this condition, ACHesterase inhibitor (Edrophonium) reverses weakness.
Myasthenia Gravis
In this condition, antibodies block ACH receptors at postsynaptic neuromuscular junction of skeletal muscles
Myasthenia Gravis
This condition is caused by deficiency in ACH storage, mobilization, re-synthesis and as muscle weakness in NEWBORN.
Congenital Myasthenia
This condition is caused by deficiency in presynaptic ACH release.
Botulinum toxin/Eaton- Lambert Myasthenic Syndrome
This substance can cause Descending weakness ( CN muscles-> shoulders->feet).
Botulinum toxin
This condition is characterized by antibodies against voltage gated Ca++ channels in the NMJ.
Eaton Lamberg Syndrome
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