What's the matter?
She's got a toothache
What's the matter?
He's got a headache
What's the matter?
She's got a stomachache
What's the matter?
She's got a runny nose/the flu/a cold.
What's the matter?
He's got an earache
What's the matter?
It's got a fever/temperature
What's the matter?
He's got a broken leg
What's the matter?
He's got a sore throat