What's the matter? (I)
I have a cold.
What's the matter? (SHE)
She has a temperature
What's the matter? (She)
She has a backache.
What's the matter? (SHE)
She has a headache
What's the matter? (I)
I have a toothache
What's the matter? (I)
I have an earache.
What's the matter? (SHE)
She has a cough.
What's the matter? (HE)
He has a stomachache