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The metabolic disease characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both.
Diabetes
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The electrolyte that must be critically assessed before giving insulin because insulin drives it into cells, risking arrhythmias.
Potassium
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The two-hour glucose level range (140–199 mg/dL) on a 75-g oral glucose tolerance test indicating prediabetes.
Impaired glucose tolerance
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The abdominal organ responsible for converting food into fuel for the body’s cells.
Pancreas
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A life-threatening complication caused by a prolonged total lack of insulin, resulting in ketone accumulation and metabolic acidosis.
DKA
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The impaired fasting glucose range defined as fasting plasma glucose between 100 and 125 mg/dL.
Impaired fasting glucose
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The critical brain condition caused by severe glucose deprivation, usually occurring when blood glucose falls below 50 mg/dL.
Neuroglycopenia
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The diagnostic blood glucose level typically seen in DKA that exceeds normal limits.
Greater than 250 mg/dL
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The blood pH value indicating acidosis in DKA.
Less than 7.3
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The highest priority intervention in DKA management before insulin administration.
Initiation of IV isotonic fluids (usually normal saline)
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The only definitive treatment for spontaneous hypoglycemia caused by hyperplastic or neoplastic pancreatic tissue.
Surgical removal of the hyperplastic or neoplastic tissue
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Deep, rapid, labored breathing observed in patients with metabolic acidosis such as DKA.
Kussmaul respirations
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The condition characterized by insufficient insulin production leading to persistent hyperglycemia.
Hypoinsulinism
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The pancreatic hormone that lowers blood sugar by moving glucose into body cells.
Insulin
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The early autonomic symptom of hypoglycemia caused by epinephrine release that results in cold sweating.
Diaphoresis
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A condition caused by inadequate pancreatic enzyme production characterized by weight loss and fatty stools.
Malnutrition
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The pancreatic hormone that raises blood sugar by signaling the liver to release stored glucose.
Glucagon
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The enzyme produced by the pancreas that breaks down carbohydrates.
Amylase
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The pancreatic function that secretes products through ducts onto an epithelium instead of directly into the bloodstream.
Exocrine function
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The condition in which continuous, unregulated insulin secretion leads to β-cell proliferation and reduced apoptosis.
Hyperinsulinism
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