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Gene Mutations

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  • What are the 4 organic bases (letters)?
    A, T, C, G
  • When only one base is substituted or deleted from a DNA sequence and the rest of the sequence stays healthy, what type of gene mutation is that?
    Point mutation
  • What type of mutation is shown given the example sentence THE FAT CAT ATE THE RAT: -- THE FTC ATA TET HER AT
    Frameshift deletion
  • What type of chromosome mutation is shown in the following image?
    Inversion
  • True/False: Mutations are always planned and can never occur randomly.
    False
  • t/f regulatory sequences only occur before (upstream) the gene
    false
  • When a mutation results in a different amino acid
    missense
  • when a mutation results in a stop codon in the middle of the gene, this is called a _________________________
    Nonsense mutation
  • how many bases are in a codon?
    three
  • true or false, an intron is coding DNA
    false
  • A mutated gene can result in a changed ______________.
    Protein
  • What are the 4 types of Chromosomal Mutations?
    Deletion, Duplication, Inversion, Translocation
  • Humans have how many chromosomes TOTAL?
    46
  • t/f regulatory sequences are coding DNA because they affect protein production
    false
  • T/F Mrs Butt thinks Pseudogenes sound interesting
    TRUE
  • Identify the following mutation using the healthy DNA sequence sample sentence that was provided in your notes: THE FAA TCA TAT ETH ERA T
    Frameshift - Insertion
  • What type of mutation affects the reading frame?
    Frameshift mutations
  • Any change in the structure or number of chromosomes is defined as:
    Chromosomal mutation
  • t/f most of your DNA codes for proteins
    false
  • In gene mutations nucleotides/bases may be what? Must say all.
    Added, missing, or changed
  • What is the amino acid(protein) for the DNA sequence - CAT
    Val
  • What is the DNA sequence for the mRNA sequence - AAG
    TTC
  • When a mutation results in no change to the amino acid sequence.
    silent mutation
  • What type of chromosomal mutation is shown in the following image:
    Duplication
  • When material is swapped with another pair of chromosomes it is defined as what tyoe of chromosomal mutation?
    Translocation
  • What percentage of your DNA codes for proteins?
    1-2 %
  • What type of mutation is shown in the following image?
    Translocation
  • Any change to the DNA sequence of a gene is defined as a:
    Gene mutation