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Gene Mutations
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What are the 4 organic bases (letters)?
A, T, C, G
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When only one base is substituted or deleted from a DNA sequence and the rest of the sequence stays healthy, what type of gene mutation is that?
Point mutation
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What type of mutation is shown given the example sentence THE FAT CAT ATE THE RAT: -- THE FTC ATA TET HER AT
Frameshift deletion
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What type of chromosome mutation is shown in the following image?
Inversion
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True/False: Mutations are always planned and can never occur randomly.
False
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t/f regulatory sequences only occur before (upstream) the gene
false
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When a mutation results in a different amino acid
missense
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when a mutation results in a stop codon in the middle of the gene, this is called a _________________________
Nonsense mutation
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how many bases are in a codon?
three
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true or false, an intron is coding DNA
false
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A mutated gene can result in a changed ______________.
Protein
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What are the 4 types of Chromosomal Mutations?
Deletion, Duplication, Inversion, Translocation
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Humans have how many chromosomes TOTAL?
46
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t/f regulatory sequences are coding DNA because they affect protein production
false
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T/F Mrs Butt thinks Pseudogenes sound interesting
TRUE
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Identify the following mutation using the healthy DNA sequence sample sentence that was provided in your notes: THE FAA TCA TAT ETH ERA T
Frameshift - Insertion
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What type of mutation affects the reading frame?
Frameshift mutations
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Any change in the structure or number of chromosomes is defined as:
Chromosomal mutation
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t/f most of your DNA codes for proteins
false
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In gene mutations nucleotides/bases may be what? Must say all.
Added, missing, or changed
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What is the amino acid(protein) for the DNA sequence - CAT
Val
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What is the DNA sequence for the mRNA sequence - AAG
TTC
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When a mutation results in no change to the amino acid sequence.
silent mutation
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What type of chromosomal mutation is shown in the following image:
Duplication
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When material is swapped with another pair of chromosomes it is defined as what tyoe of chromosomal mutation?
Translocation
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What percentage of your DNA codes for proteins?
1-2 %
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What type of mutation is shown in the following image?
Translocation
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Any change to the DNA sequence of a gene is defined as a:
Gene mutation
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