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Higher Biology - Unit 1

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  • How much of the genome is made up of regions that code for DNA?
    Around 95%
    Around 2%
    Around 50%
    All of it
  • Natural selection of human babies of medium rather than low or high mass is an example of?
    Directional selection
    Sexual selection
    Stabilising selection
    Disruptive selection
  • Name the trio who won the 1962 Nobel Prize in Medicine for their discovery of DNA's structure.
    Best, Law and Charlton
    Watson, Crick and Wilkins
    Diamond, Yauch and Horowitz
    Rowland, Knowles and Williams
  • What is the name for the basic units which make up strands of DNA?
    Sugars
    Phosphates
    Bases
    Nucleotides
  • The study of evolutionary relatedness is known as what?
    Bioinformatics
    Pharmacogenetics
    Phylogenetics
    Speciation
  • What kind of bonds form between adjacent amino acids in protein synthesis at the ribosome?
    Disulphide bridges
    Hydrogen
    Peptide
    Strong chemical
  • What word describes the process by which a cell develops more specialised functions?
    Transcription
    Replication
    Differentiation
    Translation
  • Normal DNA - ATTTTTTACG. Mutated DNA - ATTTATTTACG. Which type of mutation has occurred?
    Deletion
    Insertion
    Inversion
    Substitution
  • The two strands of DNA are held together by which kind of bonds?
    Strong chemical
    Phosphate
    Peptide
    Hydrogen
  • When part of a chromosome becomes attached to another chromosome it is known as what?
    Translocation
    Deletion
    Inversion
    Duplication
  • Substitution, insertion or deletion of a single nucleotide in a DNA sequence is known as:
    Translocation mutation
    Single gene mutation
    Chromosome structure mutation
    Polyploidy
  • Which of the following is true of RNA?
    All of the above
    Is made up of 2 strands
    Possesses the base uracil
    Contains deoxyribose
  • Which of the following is the correct order of evolution?
    cells > prokaryotes > eukaryotes > animals > land plants
    prokaryotes > cells > eukaryotes > animals > land plants
    cells > prokaryotes > animals > eukaryotes > land plants
    cells > prokaryotes > eukaryotes > land plants > animals
  • Which type of RNA carries a copy of the genetic code from the nucleus to the ribosome?
    tRNA
    zRNA
    rRNA
    mRNA
  • PCR is a technique used for what?
    The amplification of DNA in livin la vida loca
    The amplification of DNA in vivo
    The amplification of DNA in vitro
    The amplification of DNA in limbo
  • Which type of mutation would affect only one amino acid in the polypeptide produced?
    Insertion
    Deletion
    All of the above
    Substitution
  • Which type of natural selection can lead to speciation?
    Dimensional
    Disruptive
    Directional
    Stabilising
  • The main components of a ribosome are:
    mRNA and protein
    mRNA and rRNA
    rRNA and protein
    mRNA and tRNA
  • Which of the following barriers would not be involved in an example of sympatric speciation?
    Behavioural
    Ecological
    Geographical
  • What kind of cells are found in animals and produce specialised cells of one or more types?
    Stem cells
    Haploid
    Meristems
    Differentiation cells
  • 1000 DNA fragments are present at the start of a 5 min PCR cycle. How many after 20 min?
    4000
    16000
    8000
    32000
  • What parts are removed from the primary transcript when producing the mature RNA transcript?
    Exons
    Bases
    Introns
    Coding regions
  • Why can both strands of DNA not be replicated continuously?
    DNA nucleotides can only be added in a 3’ to 5’ direction
    There is not enough space for both strands to be copied
    The DNA polymerase can only act on one strand at a time
    DNA nucleotides can only be added in a 5’ to 3’ direction
  • Which of the following is NOT one of the three domains of life?
    Bacteria
    Eukaryotes
    Archaea
    Prokaryotes
  • Which type of chromosome structure mutation is important for evolution?
    Translocation
    Inversion
    Deletion
    Duplication
  • The genetic material in human mitochondria is arranged as:
    Circular plasmids
    Linear chromosomes
    Circular chromosomes
    Linear plasmids
  • Fragments of DNA which have been replicated discontinuously are joined together using what?
    Restriction endonuclease
    Ligase
    Protease
    DNA polymerase
  • Normal DNA - ATCCCCCTACC. Mutated DNA - ATCCACCTACC. Which type of mutation has occurred?
    Deletion
    Substitution
    Insertion
    Inversion
  • The insertion of an extra nucleotide into a DNA sequence results in what?
    Missense mutation
    Frameshift mutation
    Neutral mutation
    Nonsense mutation
  • During PCR, which of the following occurs at the highest temperature?
    Strands separated
    DNA polymerase adds nucleotides
    Ligase joins DNA fragments
    Primers bind
  • Which of the following are required in a polymerase chain reaction (PCR)?
    RNA polymerase, template strand and primers
    DNA polymerase, template strand and ligase
    RNA polymerase, ligase and primers
    DNA polymerase, template strand and primers
  • What are DNA nucleotides made up of?
    A ribose sugar, phosphate and ATP
    A deoxyribose sugar, phosphate and base
    A deoxyribose sugar, phosphate and ATP
    A ribose sugar, phosphate and base
  • Which of these enzymes is required for DNA replication?
    Restriction endonuclease
    Ligase
    Dehydrogenase
    Amylase
  • If a protein contains 120 amino acids then how many bases were present in the original gene?
    360
    40
    120
    60
  • Which of the following are involved in transcription of DNA but not replication of DNA?
    DNA polymerase
    Ligase
    Primers
    RNA polymerase
  • Which of the following is true of meristems?
    Specialised plant cells
    Unspecialised animal cells
    Specialised animal cells
    Unspecialised plant cells
  • Which of the following is a potential downside to stem cell research?
    They can be used to repair damaged or diseased organs
    They can be used as model cells
    They can be used to investigate how cells become specialised
    There are ethical issues surrounding their use
  • What are the DNA base pairing rules?
    Adenine to Uracil, Cytosine to Guanine
    Adenine to Cytosine, Thymine to Guanine
    Adenine to Thymine, Cytosine to Guanine
    Adenine to Guanine, Cytosine to Thymine
  • What stage of protein synthesis occurs in the nucleus?
    Formation of the final 3D protein shape
    Translation
    Transcription
    Cutting and combining
  • The process of editing a primary transcript to produce a mature RNA transcript is called what?
    Modification
    Translation
    RNA splicing
    Transcription