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Higher Biology - Unit 1
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How much of the genome is made up of regions that code for DNA?
Around 95%
Around 2%
Around 50%
All of it
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Natural selection of human babies of medium rather than low or high mass is an example of?
Directional selection
Sexual selection
Stabilising selection
Disruptive selection
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Name the trio who won the 1962 Nobel Prize in Medicine for their discovery of DNA's structure.
Best, Law and Charlton
Watson, Crick and Wilkins
Diamond, Yauch and Horowitz
Rowland, Knowles and Williams
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What is the name for the basic units which make up strands of DNA?
Sugars
Phosphates
Bases
Nucleotides
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The study of evolutionary relatedness is known as what?
Bioinformatics
Pharmacogenetics
Phylogenetics
Speciation
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What kind of bonds form between adjacent amino acids in protein synthesis at the ribosome?
Disulphide bridges
Hydrogen
Peptide
Strong chemical
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What word describes the process by which a cell develops more specialised functions?
Transcription
Replication
Differentiation
Translation
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Normal DNA - ATTTTTTACG. Mutated DNA - ATTTATTTACG. Which type of mutation has occurred?
Deletion
Insertion
Inversion
Substitution
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The two strands of DNA are held together by which kind of bonds?
Strong chemical
Phosphate
Peptide
Hydrogen
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When part of a chromosome becomes attached to another chromosome it is known as what?
Translocation
Deletion
Inversion
Duplication
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Substitution, insertion or deletion of a single nucleotide in a DNA sequence is known as:
Translocation mutation
Single gene mutation
Chromosome structure mutation
Polyploidy
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Which of the following is true of RNA?
All of the above
Is made up of 2 strands
Possesses the base uracil
Contains deoxyribose
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Which of the following is the correct order of evolution?
cells > prokaryotes > eukaryotes > animals > land plants
prokaryotes > cells > eukaryotes > animals > land plants
cells > prokaryotes > animals > eukaryotes > land plants
cells > prokaryotes > eukaryotes > land plants > animals
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Which type of RNA carries a copy of the genetic code from the nucleus to the ribosome?
tRNA
zRNA
rRNA
mRNA
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PCR is a technique used for what?
The amplification of DNA in livin la vida loca
The amplification of DNA in vivo
The amplification of DNA in vitro
The amplification of DNA in limbo
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Which type of mutation would affect only one amino acid in the polypeptide produced?
Insertion
Deletion
All of the above
Substitution
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Which type of natural selection can lead to speciation?
Dimensional
Disruptive
Directional
Stabilising
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The main components of a ribosome are:
mRNA and protein
mRNA and rRNA
rRNA and protein
mRNA and tRNA
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Which of the following barriers would not be involved in an example of sympatric speciation?
Behavioural
Ecological
Geographical
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What kind of cells are found in animals and produce specialised cells of one or more types?
Stem cells
Haploid
Meristems
Differentiation cells
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1000 DNA fragments are present at the start of a 5 min PCR cycle. How many after 20 min?
4000
16000
8000
32000
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What parts are removed from the primary transcript when producing the mature RNA transcript?
Exons
Bases
Introns
Coding regions
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Why can both strands of DNA not be replicated continuously?
DNA nucleotides can only be added in a 3’ to 5’ direction
There is not enough space for both strands to be copied
The DNA polymerase can only act on one strand at a time
DNA nucleotides can only be added in a 5’ to 3’ direction
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Which of the following is NOT one of the three domains of life?
Bacteria
Eukaryotes
Archaea
Prokaryotes
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Which type of chromosome structure mutation is important for evolution?
Translocation
Inversion
Deletion
Duplication
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The genetic material in human mitochondria is arranged as:
Circular plasmids
Linear chromosomes
Circular chromosomes
Linear plasmids
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Fragments of DNA which have been replicated discontinuously are joined together using what?
Restriction endonuclease
Ligase
Protease
DNA polymerase
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Normal DNA - ATCCCCCTACC. Mutated DNA - ATCCACCTACC. Which type of mutation has occurred?
Deletion
Substitution
Insertion
Inversion
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The insertion of an extra nucleotide into a DNA sequence results in what?
Missense mutation
Frameshift mutation
Neutral mutation
Nonsense mutation
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During PCR, which of the following occurs at the highest temperature?
Strands separated
DNA polymerase adds nucleotides
Ligase joins DNA fragments
Primers bind
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Which of the following are required in a polymerase chain reaction (PCR)?
RNA polymerase, template strand and primers
DNA polymerase, template strand and ligase
RNA polymerase, ligase and primers
DNA polymerase, template strand and primers
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What are DNA nucleotides made up of?
A ribose sugar, phosphate and ATP
A deoxyribose sugar, phosphate and base
A deoxyribose sugar, phosphate and ATP
A ribose sugar, phosphate and base
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Which of these enzymes is required for DNA replication?
Restriction endonuclease
Ligase
Dehydrogenase
Amylase
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If a protein contains 120 amino acids then how many bases were present in the original gene?
360
40
120
60
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Which of the following are involved in transcription of DNA but not replication of DNA?
DNA polymerase
Ligase
Primers
RNA polymerase
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Which of the following is true of meristems?
Specialised plant cells
Unspecialised animal cells
Specialised animal cells
Unspecialised plant cells
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Which of the following is a potential downside to stem cell research?
They can be used to repair damaged or diseased organs
They can be used as model cells
They can be used to investigate how cells become specialised
There are ethical issues surrounding their use
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What are the DNA base pairing rules?
Adenine to Uracil, Cytosine to Guanine
Adenine to Cytosine, Thymine to Guanine
Adenine to Thymine, Cytosine to Guanine
Adenine to Guanine, Cytosine to Thymine
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What stage of protein synthesis occurs in the nucleus?
Formation of the final 3D protein shape
Translation
Transcription
Cutting and combining
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The process of editing a primary transcript to produce a mature RNA transcript is called what?
Modification
Translation
RNA splicing
Transcription
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