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Higher Biology - Unit 1

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  • Name the trio who won the 1962 Nobel Prize in Medicine for their discovery of DNA's structure.
    Watson, Crick and Wilkins
    Best, Law and Charlton
    Diamond, Yauch and Horowitz
    Rowland, Knowles and Williams
  • Which of the following is NOT one of the three domains of life?
    Archaea
    Prokaryotes
    Bacteria
    Eukaryotes
  • What word describes the process by which a cell develops more specialised functions?
    Transcription
    Replication
    Differentiation
    Translation
  • What kind of cells are found in animals and produce specialised cells of one or more types?
    Haploid
    Differentiation cells
    Meristems
    Stem cells
  • Which of the following is a potential downside to stem cell research?
    There are ethical issues surrounding their use
    They can be used as model cells
    They can be used to investigate how cells become specialised
    They can be used to repair damaged or diseased organs
  • Which of the following is true of meristems?
    Unspecialised plant cells
    Unspecialised animal cells
    Specialised plant cells
    Specialised animal cells
  • The two strands of DNA are held together by which kind of bonds?
    Phosphate
    Peptide
    Hydrogen
    Strong chemical
  • Which of the following is the correct order of evolution?
    cells > prokaryotes > animals > eukaryotes > land plants
    cells > prokaryotes > eukaryotes > animals > land plants
    cells > prokaryotes > eukaryotes > land plants > animals
    prokaryotes > cells > eukaryotes > animals > land plants
  • The process of editing a primary transcript to produce a mature RNA transcript is called what?
    Modification
    Translation
    Transcription
    RNA splicing
  • Normal DNA - ATTTTTTACG. Mutated DNA - ATTTATTTACG. Which type of mutation has occurred?
    Substitution
    Inversion
    Deletion
    Insertion
  • Which of the following barriers would not be involved in an example of sympatric speciation?
    Behavioural
    Ecological
    Geographical
  • Fragments of DNA which have been replicated discontinuously are joined together using what?
    Protease
    Ligase
    DNA polymerase
    Restriction endonuclease
  • Which of the following are required in a polymerase chain reaction (PCR)?
    DNA polymerase, template strand and ligase
    RNA polymerase, template strand and primers
    DNA polymerase, template strand and primers
    RNA polymerase, ligase and primers
  • PCR is a technique used for what?
    The amplification of DNA in vitro
    The amplification of DNA in limbo
    The amplification of DNA in livin la vida loca
    The amplification of DNA in vivo
  • Which type of mutation would affect only one amino acid in the polypeptide produced?
    Deletion
    Substitution
    Insertion
    All of the above
  • What are the DNA base pairing rules?
    Adenine to Thymine, Cytosine to Guanine
    Adenine to Cytosine, Thymine to Guanine
    Adenine to Guanine, Cytosine to Thymine
    Adenine to Uracil, Cytosine to Guanine
  • Which of these enzymes is required for DNA replication?
    Dehydrogenase
    Ligase
    Amylase
    Restriction endonuclease
  • How much of the genome is made up of regions that code for DNA?
    All of it
    Around 2%
    Around 95%
    Around 50%
  • Natural selection of human babies of medium rather than low or high mass is an example of?
    Stabilising selection
    Directional selection
    Sexual selection
    Disruptive selection
  • 1000 DNA fragments are present at the start of a 5 min PCR cycle. How many after 20 min?
    4000
    32000
    8000
    16000
  • Normal DNA - ATCCCCCTACC. Mutated DNA - ATCCACCTACC. Which type of mutation has occurred?
    Deletion
    Insertion
    Inversion
    Substitution
  • What is the name for the basic units which make up strands of DNA?
    Sugars
    Phosphates
    Nucleotides
    Bases
  • The insertion of an extra nucleotide into a DNA sequence results in what?
    Missense mutation
    Frameshift mutation
    Nonsense mutation
    Neutral mutation
  • If a protein contains 120 amino acids then how many bases were present in the original gene?
    60
    360
    40
    120
  • The genetic material in human mitochondria is arranged as:
    Linear chromosomes
    Circular chromosomes
    Circular plasmids
    Linear plasmids
  • Why can both strands of DNA not be replicated continuously?
    The DNA polymerase can only act on one strand at a time
    There is not enough space for both strands to be copied
    DNA nucleotides can only be added in a 5’ to 3’ direction
    DNA nucleotides can only be added in a 3’ to 5’ direction
  • When part of a chromosome becomes attached to another chromosome it is known as what?
    Duplication
    Inversion
    Deletion
    Translocation
  • During PCR, which of the following occurs at the highest temperature?
    DNA polymerase adds nucleotides
    Primers bind
    Ligase joins DNA fragments
    Strands separated
  • Which type of chromosome structure mutation is important for evolution?
    Inversion
    Translocation
    Deletion
    Duplication
  • What kind of bonds form between adjacent amino acids in protein synthesis at the ribosome?
    Strong chemical
    Hydrogen
    Peptide
    Disulphide bridges
  • What parts are removed from the primary transcript when producing the mature RNA transcript?
    Coding regions
    Exons
    Bases
    Introns
  • Which of the following is true of RNA?
    Is made up of 2 strands
    All of the above
    Contains deoxyribose
    Possesses the base uracil
  • Substitution, insertion or deletion of a single nucleotide in a DNA sequence is known as:
    Single gene mutation
    Polyploidy
    Translocation mutation
    Chromosome structure mutation
  • What are DNA nucleotides made up of?
    A deoxyribose sugar, phosphate and base
    A deoxyribose sugar, phosphate and ATP
    A ribose sugar, phosphate and base
    A ribose sugar, phosphate and ATP
  • Which type of RNA carries a copy of the genetic code from the nucleus to the ribosome?
    rRNA
    tRNA
    zRNA
    mRNA
  • What stage of protein synthesis occurs in the nucleus?
    Translation
    Formation of the final 3D protein shape
    Cutting and combining
    Transcription
  • Which of the following are involved in transcription of DNA but not replication of DNA?
    DNA polymerase
    Ligase
    RNA polymerase
    Primers
  • The main components of a ribosome are:
    rRNA and protein
    mRNA and protein
    mRNA and rRNA
    mRNA and tRNA
  • The study of evolutionary relatedness is known as what?
    Pharmacogenetics
    Bioinformatics
    Phylogenetics
    Speciation
  • Which type of natural selection can lead to speciation?
    Stabilising
    Directional
    Dimensional
    Disruptive