What's the matter with him?
He has a headache
What's the matter with him?
He is sick
What's the matter?
She has a headache.
What's the matter?
She has a cold.
What's the matter with her?
She has a cough
What's the matter with him?
He has a toothache
What's the matter with him?
He has a stomachache
What's the matter?
He has a toothache.
What's the matter with her?
She has a cold
What does he have?
A cast
What's the matter with her?
She is tired