What's the matter with him?
He has a food allergy.
What's the matter with the Dog?
The dog has a cold/fever.
What's the matter with her?
She has pink eye
What's the matter with him?
He has chicken pox.
What's wrong with the fox?
The fox has chicken pox
What's the matter with the dog?
The dog has a stomachache
What's the matter with her?
She has a fever
What's the matter with him?
He has diarrhea
What's the matter with the panda?
The panda has a headache