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Autoimmune riddles
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I have keys without keylock. I have space without room. You can enter but cannot go outside.
keyboard
Take away my skin and I will not cry, but you will. What am I?
an onion
Secondary immune response against self antigen different from and not cross-reactive with the epitope of primary antigen is known as ...
epitope spreading
Beside apoptosis, what can happen to a self reactive T cell in the thymus?
Differentiate into Treg
A man who was outside in the rain without an umbrella or any other covering didn't get a single hair on his head wet. Why?
He's bald
What can you catch but not throw?
a cold
Mention 2 immunologically privileged sites!
brain, eye, testis, uterus
What do you called the activation of T lymphocytes that are not specific for an infectious pathogen at the same time with infection?
bystander activation
What will happen if self reactive T cell is repeatedly activated in peripheral tissue?
Apoptosis
I always come but never arrive. What am I?
Tomorrow
A boy and an engineer were fishing. The boy is the son of the engineer but the engineer is not the father of the boy. How is that possible?
The engineer is the boy's mother
What happen when B cell in bone marrow recognizes self antigen?
Receptor editing, followed by apoptosis if there's a failure in editing process
What will happen if self reactive T cell recognizes self antigen without the presence of co-stimulatory molecules?
anergy
What hormone can downregulate AIRE gene expression?
estrogen
What belongs only to you, and yet is used more by others than by yourself?
Your name
A pathogen has antigen that looks like self antigen, thus, immune response elicited against pathogen also reacts against self antigen. What do you called this phenomenon?
molecular mimicry
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