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Autoimmune riddles

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    Autoimmune & fun riddles
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  • A pathogen has antigen that looks like self antigen, thus, immune response elicited against pathogen also reacts against self antigen. What do you called this phenomenon?
    molecular mimicry
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  • What belongs only to you, and yet is used more by others than by yourself?
    Your name
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  • What hormone can downregulate AIRE gene expression?
    estrogen
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  • What will happen if self reactive T cell recognizes self antigen without the presence of co-stimulatory molecules?
    anergy
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  • What happen when B cell in bone marrow recognizes self antigen?
    Receptor editing, followed by apoptosis if there's a failure in editing process
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  • A boy and an engineer were fishing. The boy is the son of the engineer but the engineer is not the father of the boy. How is that possible?
    The engineer is the boy's mother
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  • I always come but never arrive. What am I?
    Tomorrow
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  • What will happen if self reactive T cell is repeatedly activated in peripheral tissue?
    Apoptosis
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  • What do you called the activation of T lymphocytes that are not specific for an infectious pathogen at the same time with infection?
    bystander activation
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  • Mention 2 immunologically privileged sites!
    brain, eye, testis, uterus
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  • What can you catch but not throw?
    a cold
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  • A man who was outside in the rain without an umbrella or any other covering didn't get a single hair on his head wet. Why?
    He's bald
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  • Beside apoptosis, what can happen to a self reactive T cell in the thymus?
    Differentiate into Treg
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  • Secondary immune response against self antigen different from and not cross-reactive with the epitope of primary antigen is known as ...
    epitope spreading
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  • Take away my skin and I will not cry, but you will. What am I?
    an onion
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  • I have keys without keylock. I have space without room. You can enter but cannot go outside.
    keyboard
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