What is the matter with her?
She has got a allergy to pollen / She is allergic to pollen.
What is the matter with you when you use earphones too much?
You will have an earache.
What is the matter with him? What should he do now?
He has got a sore throat.
What is the matter with her? Why has she got sick?
She has got a toothache because ...
What is the matter with them? What should they do now?
They have a cough.
What is the problem with her? What should she do now?
She has sore eyes.
What is the matter with her? What should she do now?
She has a diarrhoea
What is the matter with the penguin? What should it do now?
It has got a headache.
What is the matter with her? What should she do now?
She has got a runny nose.
What is the problem with her? What should she do now?
She cuts her hand and it is bleeding.
What is the problem with her? What should she do now?
She has a backache / Her back is hurt.
What is the matter with him? What should he do now?
He has got a fever.