Myopathy | Baamboozle - Baamboozle | The Most Fun Classroom Games!

English 21 Public

muscle disease

Study Slideshow

Which muscle type is more dependent on fat catabolism for energy through mitochondrial oxidative phosphorylation

Type 1

Disuse- and steroid-induced atrophy primarily affects which TYPE fibers and causes a random distribution of the atrophic myofibers

Type 2

Grouped muscle atrophy is a hallmark of which type of atrophy

Neurogenic atrophy

what are three x-linked Dystrophic Myopathies

Duchenne/Becker/Emery Dreifuss

Histologically, in advanced cases muscle fibers are replaced by fibrofatty tissue in which condition

Muscular dystrophy

What are three histolology features of Duchenne Dystropy

Muscle size variation, absent of dystrophin, incr connective tissue, regeneration, fiber loss, adipose infiltration

Besides muscle, which other tissue is dystrophin found in?

Brain and nerves

Name 3 x-linked muscular dystrophy conditions

duchenne's Becker, Emery-Dreifuss

This sign describes a patient that has to use their hands and arms to "walk" up their own body from a squatting position due to lack of hip and thigh muscle strength.

Gower's sign

Patient with this condition has Distal> proximal muscle weakness, frontal balding, hatchet face, cardiac endocrine abnormality

Myotonic Dystrophy

Patient with this condition can move eyes freely but has retinopathy, facial weakness, frontal balding, lip protrusion .

FSH ( Landouzy-Dejerine)

This 60 y.o. with RA , developed progressive proximal muscle weakness but normal EMG. What is likely condition?

Steroid myopathy

In this Autosomal recessive muscle dystrophy, patient has UE and LE proximal weakness and scattered fiber necrosis and regeneration seen on muscle biopsy

Limb Girdle

Name 2 conditions that could cause this.

Central core, centronuclear myotubular,nemaline rod, fiber disproportion

This patient is at risk formalignant hyperthermia due to absent of ---- in type 1 fibers

Central core- absent of mitochondria

This patient has difficulty getting up from a chair or climbing steps

Dermatomyositis