Do ABO antibodies require the use of potentiators in vitro?
NO
5
What conditions are associated with acquired B antigen?
Group A1 individuals with disease of lower GI tract
15
Which transferase does A allele produce?
N-acetylgalactosaminyltransferase The A allele produces N-acetylgalactosaminyltransferase, which transfers the sugar, N-acetylgalactosamine, to an
15
Which blood type has the most H antigens?
O __ As a result, group O red cells carry no A or B antigens but are rich in unconverted H antigens.
10
Does anti A2 exist?
No-A1 phenotype do not respond immunologically when exposed to A2 red cells.
15
A trauma patient with type AB is seen at a rural hospital. The hospital has only 3 units AB RBC's. What blood type of RBC's can the patient receive as an alternative?
Any
10
How many molecules of IgM are needed to activate complement?
1
10
A recipient with group A phenotype requires a transfusion of 2 units of frozen plasma. Which types are appropriate to select for transfusion?
AB and A
10
A group A man marries a group AB woman. The father of the group A man was group O. What possible ABO phenotypes could be expected in the offspring?
Group A, B and AB
15
Predict the agglutination reaction of red cells from a Bombay phenotype when combined with anti-H lectin.
Negative
10
The weak D test detects:
A weak D antigen.
5
Anti-D reagent and the D control were tested with patient’s red cells. Both tests were 2+ agglutination reactions. What is the interpretation of the results?
Unable to interpret without further testing/ Invalid
5
What is the next step in the investigating a positive DAT after testing with polyspecific AHG?
Repeat the direct antiglobulin test using monospecific anti-IgG and anti-C3 reagents.
10
In an antibody identification panel, only one red cell was negative at the antihuman globulin phase. On ruling out and matching the pattern, an anti-k was identified. What further testing is necessary to confirm the antibody?
Two more k-negative cells should be tested.
20
IgG sensitized cells are also called?
Check cells
5
The term used to describe the biochemical and morphologic changes that occur when blood is stored at 1-6 degrees C :