What is it called when a medication is given and on first pass through the liver gets inactivated
first-pass effect
What is the time for a medication in the body to drop by 50%?
half-life
Medication that binds to or mimics receptor activity that endogenous compounds regulate.
Agonist
Getting this drug as a kid when they have a viral illness can cause Reyes Syndrome.
Aspirin
A patient got morphine for pain an hour ago and now their respirations are 8/min. What should you do?
Give naloxone
With this antibiotic, you must monitor them for 30 min. after administration to look for allergic reaction.
penicillin
This antibiotic is used to treat c-diff and can potentially cause red-man syndrome if given IV.
vancomycin
What antibiotic can cause yellow-brown tooth discoloration, photosensitivity, and hepatotoxicity?
tetracycline
What class of antibiotics can cause ototoxicity and nephrotoxicity?
aminoglycosides
What class of antibiotics can cause achilles tendon rupture, phototoxicity, and suprainfection?
fluoroquinolones
Antifungal used to treat systemic fungal infection that requires premedication for fever, chills, and headache before you give it.
amphotericin B
What 3 antiviral tubercular drugs can all cause hepatotoxicity?
rifampin, isoniazid, pyrazinamide
What is it called when someone has a secondary infection superimposed on another infection where a person could suffer from thrush or a vaginal yeast infection?
superinfection
What is the main organ involved in excretion?
kidneys
Where does most of metabolism take place?
liver
What class of HIV drugs is considered a first-line treatment for HIV infection and works by inhibiting DNA synthesis?
NRTIs
