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cells of the immune sytem
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Phagocytic cells are studded with plasma membrane proteins known as toll-like receptors (TLRs) that recognize __________typically found on viral and bacterial cell walls.
pathogen-associated molecular patterns (PAMPs)
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Macrophages and other phagocytic cells detect pathogens by their _________
Toll like receptors TLR's
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Plasma cells swell as they add large amounts of the organelle known as ___________ for protein production
endoplasmic reticulum
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Type of leukocytes that respond to antigens only when they are bound to specific molecules called major histocompatability complex (MHC) proteins
T cells
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The type of MHC molecules that are found and antigen presenting cells (APCs) such as macrophages and dendritic cells
MHC II
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The type of MHC molecules that are found on all nucleated human cells and are the proteins that are the cell’s self-antigens.
MHC I
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What type of receptors are found on T cells
TCRs T cell receptors
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What type of receptors are found on B cells
BCRs ( B cell receptor)
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3 types of T lymphocytes
killer T, helper T, suppressor T
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Type of leukocyte that kill virus-infected and cancerous cells. Can differentiate into many other cells (killer T, helper T, suppressor T)
T lymphocytes
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professional antigen presenting cells are
macrophages, dendritic cells and B cells
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Neutrophils, basophils, and eosinophils are all considered to be _______ that can be found circulating in the bloodstream
PMNs or polymorphonuclear leukocytes
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3 actively phagocytic cells are...
dendritic cells, macrophages, neutrophils
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Are specialized antigen presenting cells (APCs) that when activated present the antigens to lymphocytes to activate them.
dendritic cells
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 when activated these cells present the antigens to lymphocytes to activate them. They include macrophages and B cells.
antigen presenting cells (APC'S)
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Type of cells that are found in the connective tissue of skin, lungs, and the gastrointestinal tract have a similar function as basophils in that they can release histamine and heparin.
mast cells
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derived from monocytes, These cells remain is a particular tissue; Example: alveolar macrophages, kupffer cells in liver, microglia
fixed monocytes
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derived from monocytes and roam tissues and gather at sites of infection and inflammation.
wandering macrophages
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Type of leukocytes that migrate from blood into tissues where they enlarge and become macrophages that are active phagocytes.
monocytes
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General term for the type of leukocytes responsible for cell-mediated immunity.
T lymphocytes
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Type of leukocyte that kill virus-infected and cancerous cells.
Cytotoxic T lymphocytes
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Type of leukocyte responsible for antibody-mediated or humoral immunity
B lymphocyte
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Type of leukocyte that differentiates into plasma cells and secrete antibodies (immunoglobulins)
B lymphocyte
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Type of agranular leukocyte with dark U or kidney-shaped nucleus
monocyte
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The fourth most common type of leukocyte in a normal blood sample.
eosinophil
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The third most common type of leukocyte in a normal blood sample.
monocyte
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The second most common type of leukocyte in a normal blood sample.
lymphocyte
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Type of leukocyte that circulate in the blood and have granules that contain histamine - a vasodilator and heparin - an anticoagulant
basophil
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Type of leukocyte that help reduce the severity of allergy attacks by phagocytosing the immune complexes; kill parasites such as flatworms
eosinophils
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Type leukocyte that increase in number during an allergy attack
eosinophils
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The type of large bone marrow cell that forms platelets
megakaryocytes
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Immature neutrophils are sometimes called
bands
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Type of leukocytes that can increase in number during an acute bacterial infection. These dead cells along with cell debris, and fluid can accumulate as pus at sites of infections
neutrophils
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___ or PMNs, are a special family of white blood cells that includes immune cells known as neutrophils, eosinophils, and basophils.
polymorphonuclear leukocytes
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Leukocytes are formed in the _______ by a process of leukopoiesis
red bone marrow
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General term for the type of cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
leukocytes
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