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acid base balance
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Severe lung disease (emphysema), uncontrolled diabetes, aspirin overdose, prolonged diarrhea, starvation, drinking an excessive amount of alcohol, or drinking antifreeze can cause urine to become more
acidic
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A normal odor for urine is a slightly "___________" (aromatic) smell. Some foods (such as asparagus), vitamins, and antibiotics (such as penicillin) can cause urine to develop an unusual odor
NUTTY!!!
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Bilirubin is not water soluble so it is transported bound to _____________ which makes is more water soluble and is transported to the liver for excretion in bile.
albumins
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Stercobilins and urobilins (urochorme) are derived from a breakdown product of blood known as
bilirubin
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The 3 principle ketones are...
acetone, beta hydroxybutyric acid and acetoacetic acid
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an increase in H+ will drive the equilibrium to the ____ resulting in a smaller net increase of acidity.
left
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If there is a decrease in H+ then this would drive the equilibrium reaction to the ____________
right
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Name the acid base related condition that can result from excessive H+ loss through the kidneys.
metabolic alkolosis
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Name the acid base related condition that can result from a loss of stomach acid as can occur during vomiting or gastric suctioning
metabolic alkalosis
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Name the acid base related condition that can be caused by excessive diarrhea
metabolic acidosis
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Name the acid base related condition that can result from hyperventilation due to anxiety
respiratory alkalosis
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Name the acid base related condition that can result from prolonged constipation.
metabolic alkalosis
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The term used to describe the transport of materials such as ions between tubule cells.
paracelluular transport
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the _________ maintain the hypertonicity of the renal medulla by a mechanism known as countercurrent exchange
vasa recta
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Name the of the nitrogenous waste products that are breakdown of purines.
uric acid
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Category of diuretics that block the reabsorption of Na+ of the ascending end of loop of Henle. More specifically it blocks the Na+/K+/2Cl- channels (NKCC) which are cotransporter (symporter) channels in the apical cells membrane.
loop diuretics
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Aquaporins are put into the apical membrane of what specific cells in response to ADH?
principle cells
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Term for the extensions of the peritubular capillaries that are long vessels that parallel the loops of Henle of the nephrons
vasa recta
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In the process of Tubuloglomerular feedback, as GFR decreases, ATP release from macular densa cells decreases, causing __________of the afferent arterioles
vasodilation
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Part of the nephron that functions in the reabsorption of NaCl and water and contains a descending and ascending limb. More specifically it contains Na+/K+/2Cl- channels (NKCC).
loop of henle
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Type of cotransport mechanism that move two or more substrates in opposite directions across the membrane.
antiport
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Blood flow through both kidneys is about ______________________. Means that all the blood passes through the kidneys every 4-5 minutes
1200 mL/min
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The ureters move urine from the pelvis to the urinary bladder by a process called ___________________
peristalsis
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A person is brought to the ER after passing out in a local department store. The person has been fasting and has ketones in the urine. The person has the following ABGs: pH = 7.34 PaCO2 = 43 mmHg HCO3 = 21. What is their ABG related illness
uncompensated metabolic acidosis
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A patient has the following arterial blood gases: pH = 7.50 HCO3 = 38 mEq/L PaCO2 = 50 mmHg. What sign/symptom might this patient exhibit as a compensatory mechanism?
hypoventilation
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Diabetic ketoacidosis, renal failure and aspirin toxicity can result in
metabolic acidosis
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You are caring for a patient with type I diabetes and a serum BG of 450 mg/dL. What pH would you see on an ABG?
below 7.35
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A patient is in metabolic acidosis d/t diabetic ketoacidosis. which signs S/S would you expect to see in this patient?
high Blood glucose, kusshmaul's breathing, disoriented
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You are caring for a patient with severe pain and a respiratory rate of 32 breaths/min. The normal respiration rate for an adult at rest is 12 to 20 bpm. Which acid-base imbalance would your expect to find with sustained tachypnea?
respiratory alkolosis
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