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DORV, Epstein Anomaly, and TOF
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TOF: Pulmonary blood flow is dependent on?
PDA and or MAPCAS.
TOF: Are they ductal dependent? If so, why?
Depends: Pulm atresia/ severe pulm stenosis=RVOTO, and needs PDA
How do we resolve a Tet spell?
Increase SVR: knees to chest (inc. SVR), vasoconstrictors (vaso/phenyl), & sedation
What is a tet spell?
an episode of acute, severe right-to-left shunting
TOF: If SVR increases (squatting, knees-to-chest, pain-induced vasoconstriction), it becomes more difficult for blood to
enter the aorta, Qs decreases while Qp increases. PBF improves.
In TOF: blood exiting the RV must choose between (2):
1. Pulmonary circulation (thru narrowed RVOT) or 2. Systemic circulation (across VSD into the overriding aorta)
TOF:  If SVR decreases, it becomes easier for blood to flow...?
into the aorta. Qs improves. More blood is shunted to the right --> left across the VSD. Qp decreases. Oxygenation worsens. Tet spell!
TOF: what happens if the atrial septum is intact?
No RA -> LA decompression, no back-up mixing route. Qp/Qs becomes dependant on RVOTO & SVR. Sm. changes in preload, afterload, or PVR = desat + cardiac output
Everything we see at the bedside comes from how blood chooses the path of ___ ___ through these structures
least resistance
Tetrology of Fallot has 4 linked problems:
RVOT obstruction (PS/PA), VSD, overriding aorta (over RV), RV hypertrophy https://upload.medbullets.com/topic/120002/images/tof-updated.jpg