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Autoimmunity an hypersensitivity
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Immune complex hypersensitivity is classified as Type III.
True
Antihistamines are absolutely safe for use in all stages of pregnancy.
False, many antihistamines cross the placenta; some are contraindicated, especially in the first trimester.
The most common allergen causing allergic contact dermatitis worldwide is nickel.
True
Serum sickness typically develops 1-2 weeks after exposure to a drug or antiserum.
True
Inhaled corticosteroids are used cautiously in TB because they suppress local lung immunity.
True, they may allow latent TB to reactivate and worsen infections.
Epinephrine reverses anaphylaxis by bronchodilation, vasoconstriction, and improved cardiac output.
True, epinephrine acts on α- and β-adrenergic receptors to counteract anaphylaxis.
Delayed-type hypersensitivity is mediated by T-lymphocytes.
True
Cytotoxic hypersensitivity (Type II) is mediated by immune complexes deposited in tissues.
False : Type II is due to IgG/IgM binding directly to cells; Type III involves immune complex deposition.
Breast milk provides natural active immunity to infants.
False, Breast milk provides **natural passive immunity** through IgA antibodies.
Natural immunity provides immediate and specific defense.
False, Natural (innate) immunity is fast but not antigen-specific.
Plasma cells are derived from activated B lymphocytes.
True, Once activated, B cells differentiate into plasma cells that secrete antibodies.
Autoimmunity occurs when the immune system succeeds to distinguish between self and non-self.
False, Autoimmunity arises from the immune system mistakenly attacking its own tissues.
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