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Pharm Week 13
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What is amiodarone used to treat?
Life threatening ventricular arrythmias.
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What is the chief neurotransmitter for the sympathetic nervous system?
Norepinephrine
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What is the chief neurotransmitter for the parasympathetic nervous system?
Acetylcholine
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True or false, Adrenergic receptors work for the parasympathetic nervous system?
False, Adrenergic receptors work for the sympathetic nervous system while cholinergic receptors work for the parasympathetic nervous system.
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Adverse effects associated with the use of cholinergic drugs include what?
Diarrhea and urinary urgency
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Name a drug used to treat Alzheimers.
donepezil (Aricept)​, galantamine (Razadyne)​, rivastigmine (Exelon)
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Name a nonselective beta blocker.
Propranolol, Timolol
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Which branch of the nervous system is responsible for rest and digest?
Parasympathetic Nervous System
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What are the four can't items of anticholinergic therapy?
Can't see, can't pee, can't spit, can't poop
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What are some AE of anticholinergics?
Blurred vision, dry mouth, slowed GI motility, pupil dilation, weakness confusion and insomnia
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Which drugs block acetylcholine?
Atropine, Scopolamine, Meclizine, Ipratropium, Oxybutynin
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Which drugs can be used to treat bronchospasms?
Albuterol, Isoproterenol, Formoterol, Salmeterol, Terbutaline
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What two receptors represent the cholinergic receptor?
Muscarinic Receptors and Nicotinic Receptors
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What do Beta-3 receptors do?
Relax bladder muscles
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What do Beta-2 receptors do?
Vasodilation, bronchi dilation, increase glycogen breakdown, increase glucagon release, relax uterus
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What do Beta-1 receptors do?
Increase HR, increase fat breakdown for energy
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What do Alpha-2 receptors do?
Prevent overstimulation of norepinephrine, control insulin release.
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What do Alpha-1 receptors control?
Vasoconstriction, raising BP, pupil dilation, closure of bladder sphincter
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What are the divisions of the ANS?
Sympathetic and Parasympathetic
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What body function are regulated by the ANS?
Fluid balance, pupil size, digestive functions, urinary excretion, temp, RR, HR, BP
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