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Pharm Week 13
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What is amiodarone used to treat?
Life threatening ventricular arrythmias.
What is the chief neurotransmitter for the sympathetic nervous system?
Norepinephrine
What is the chief neurotransmitter for the parasympathetic nervous system?
Acetylcholine
True or false, Adrenergic receptors work for the parasympathetic nervous system?
False, Adrenergic receptors work for the sympathetic nervous system while cholinergic receptors work for the parasympathetic nervous system.
Adverse effects associated with the use of cholinergic drugs include what?
Diarrhea and urinary urgency
Name a drug used to treat Alzheimers.
donepezil (Aricept)​, galantamine (Razadyne)​, rivastigmine (Exelon)
Name a nonselective beta blocker.
Propranolol, Timolol
Which branch of the nervous system is responsible for rest and digest?
Parasympathetic Nervous System
What are the four can't items of anticholinergic therapy?
Can't see, can't pee, can't spit, can't poop
What are some AE of anticholinergics?
Blurred vision, dry mouth, slowed GI motility, pupil dilation, weakness confusion and insomnia
Which drugs block acetylcholine?
Atropine, Scopolamine, Meclizine, Ipratropium, Oxybutynin
Which drugs can be used to treat bronchospasms?
Albuterol, Isoproterenol, Formoterol, Salmeterol, Terbutaline
What two receptors represent the cholinergic receptor?
Muscarinic Receptors and Nicotinic Receptors
What do Beta-3 receptors do?
Relax bladder muscles
What do Beta-2 receptors do?
Vasodilation, bronchi dilation, increase glycogen breakdown, increase glucagon release, relax uterus
What do Beta-1 receptors do?
Increase HR, increase fat breakdown for energy
What do Alpha-2 receptors do?
Prevent overstimulation of norepinephrine, control insulin release.
What do Alpha-1 receptors control?
Vasoconstriction, raising BP, pupil dilation, closure of bladder sphincter
What are the divisions of the ANS?
Sympathetic and Parasympathetic
What body function are regulated by the ANS?
Fluid balance, pupil size, digestive functions, urinary excretion, temp, RR, HR, BP