Norepinephrine: alpha, beta 1, or beta 2?
Dose: 0.01-1 mcg/kg/min. Peripheral vasc effect: alpha | Cardiac: B1
Epinephrine: alpha, beta 1, or beta 2?
Depends on dose. Low: 0.01-0.1 mCg/kg/min: peripheral vasc. effect: alpha & beta 2. Cardiac effect: B1&B2. Mod: 0.1-0.5 mCg/kg/min: alpha | B1&B2
What does the adrenergic receptor: Beta 1 do when activated in an endothelial cell?
Vasoconstricts
Isoproterenol: alpha, beta 1, or beta 2
Dose: 0.01-1 mcg/kg/min. Peripheral vasc effect: B2. Cardiac effect: B1 and B2.
Phenylephrine: alpha, beta 1, or beta 2?
Dose: 0.01 mCg/kg/min- 1 mCg/kg/min. Peripheral vasc. effect: Alpha
What does the adrenergic receptor: Beta 2 do when activated in an endothelial cell?
Vasodilates
What does the adrenergic receptor: Beta 1 do when activated in a cardiomyocyte?
Enhances contractility (inotropic) and HR (chronotropic)
I'm phosphodiesterase III inhibitor, systemic venodilator, increases contractility, and decreases atrial pressure & SVR
Milrinone
I'm a potent vasoconstrictor via the vasopressin receptor on arterioles, and no cardiac effect
Vasopressin
I spontaneously release nitric oxide causing venodilation. I decompose into cyanide. Always check my syringe to make sure I'm not blue!
Nitroprusside
I'm a class IB Na channel blocker. I slow ventricular conduction. I'm mostly used for ventricular tachycardias.
Lidocaine
I'm a class II: selective B-1 adrenergic BLOCKER (heart). I'm used for reentrant SVT and Ventricular tachycardia. You'll see me used lots on patients after a TOF repair.
Esmolol
I'm a class III antiarrhythmic: inhibit adrenergic stimulation, possesses alpha and beta-adrenergic blocking properties. Affects sodium, potassium, and calcium channels. Decreases AV conduction and sinus node fx. SVT, VT, Afib, and Vfib
Amiodarone - rapid administration may precipitate in circulatory collapse
