What's the matter? What should he do?
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What's the matter? What should she do? What shouldn't she do?
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What's wrong with him? What can he do?
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What is wrong with her? What should and shouldn't she do?
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What's the matter?
He has a headache.
What problem is this?
It's toothache.
What problem is this?
It's stomach ache. / It's an upset stomach.
What problem is this?
spots
What problem is this?
earache
What problem is this?
backache
What problem is this?
mosquito bite
What problem is this?
blisters
What's the matter?
sunburn
How does he feel?
He feels sick
