What stimulates the primary immune response in blood?
Exposure to antigen
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15
Does temperature of reaction affect agglutination? What temp do we find clinically significant reactions?
Yes, clinically significant reactions occur at 37C
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15
Part of daily QC in blood bank laboratory is the testing of reagent antisera with corresponding antigen positive and antigen negative red cells. What does this procedure ensure?
Antibody specificity and potency
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10
What immunoglobulin class reacts best by antiglobulin testing?
IgG
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15
What temperature does IgM react best at?
Room Temp 20-22 degrees C or lower
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5
What temperature is used for incubation in the indirect antihuman globulin test?
37 degrees C
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20
What does sensitized mean?
Immunoglobulin or complement attached to cell
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5
What is detected by agglutination or hemolysis at the completion of testing?
Antigen-Antibody reactions
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15
Where will I find the limitations of my AHG reagent?
Product insert/ package insert
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15
What is the immediate spin phase?
Immediately following centrifuging room temp
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baam
Lose 15 points!
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rocket
Go to first place!
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shark
Other team loses 20 points!
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baam
Lose 20 points!
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10
What is zeta potential?
Force of repulsion between RBC's
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15
What characteristic is associated with polyspecific AHG?
