A-B toxins; membrane-disrupting toxins (leukocidins, hemolysins, streptolysins), genotoxins, superantigens are all endotoxins or exotoxins?
exotoxins
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15
experimental requirements for identifying the agent of an infectious disease
Koch's postulates
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25
What are ways viruses cause cytopathic effects in the cell?
stop cell synthesis, cause cell to release lysosomes, create inclusion bodies, fusing cells to create syncytium, chromosomal changes, loss of contact inhibition
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15
What virulence factor triggers endocytosis?
invasins
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trap
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magnet
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Analytical epidemiology: analyzes a particular disease to determine its probable cause, give an example of what an analytical epidemiologist would study
investigating an outbreak of 40 staff getting food poisoning in a hospital, finding what caused the outbreaking
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boom
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seesaw
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How would you define cytopathic effects of viruses?
Cytopathic effects are visible signs in a host cell of a viral infection
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explain the 5 stages of the development of disease
incubation, prodromal, period of illness, period of decline, convalescence
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10
What are 3 portals of entry
mucous membranes, skin, parenteral route
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25
Why does the influenza vaccine only offer a few months of protection?
antigenic variation; influenza alters its surface antigens so antibodies formed from the previous vaccination do not bind to the new antigens.
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15
compare and contrast contact and vehicle transmissions and give examples
contact transmision includes direct, indirect contact, droplet and congenital transmissions, vehicleย Transmission are by an inanimate reservoir- air food water
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causes gas gangrene, tetnus, botulism, diptheria, scarlet fever, cyanobacterial intoxification
exotoxins
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25
Most organisms cannot penetrate intact skin; how then would pathogens enter a host through this portal of entry
they would enter through the hair follicles and sweat glands on the skin