Immune Baamboozle | Baamboozle - Baamboozle | The Most Fun Classroom Games!

Describe an urticarial lesion

wheals/hives - migratory, elevated, pruritic, reddish plaques caused by local dermal edema.

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Do CD8+ killer T-cells recognize MHC I or II?

MHC I

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Define Type I hypersensitivity reaction

reaction mediated by IgE antibodies.

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In Toxicodendron Dermatitis, does the fluid within a bullae contain urushiol?

No.

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how do you diagnose toxicodendron dermatitis?

Clinically by look of skin and by HPI from patient but no need for special testing (skin test)

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What is humoral immunity?

adaptive immunity where B cells secrete antibodies

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What is cell mediated immunity?

adaptive immunity which is mediated by activated, antigen-specific T cells

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General mechanism of action for a corticosteroids

downregulate expression of inflammatory cytokines, reduce activity immune system

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most common signs and symptoms of poison ivy dermatitis are

Intense itching; Skin swelling and blisters; Skin redness

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About how many hours does it usually take to develop an itchy rash from urushiol oil?

24-48 hours (delayed response)

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banana

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gift

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fairy

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baam

Lose 20 points!

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What is the elicitation phase in allergic contact dermatitis?

Re-exposure to haptens->type IV hypersensitivity reaction-> sensitized Tcells circulate to skin where antigen is

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What do macrophages release that cause changes in the skin and what changes do we see?

proinflammatory cytokines (TNF, IL-1, IL-6) --> leaky endothelial barrier = edema + redness

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seesaw

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star

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gift

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banana

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Do CD4+ helper T-cells recognize MHC I or II?

MHC II

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seesaw

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shark

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gift

Win 20 points!

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thief

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