Unit 4 SIGS cases 7-12

Help

Describe the effect HIV has on CD4+ T-cells.

HIV ->CD4 TH17 (activate neutrophils/protect mucoepithelium) is depleted->decrease CD4 T-> decrease TH1->not enough CD8T = infection + no control of infections

Identify the antiviral therapies for HIV and describe their site of action: Dolutegravir, Abacavir, Efavirenz

abacavir: NRTI-nucleoside reverse transcriptase inhibitor; dolutegravir: Integrase inhibitor; Efavirenz: NNRTI-Non-nucleoside reverse transcriptase inhibitors

Discuss the laboratory tests that guide antiretroviral drug selection: HLA-B5701 & HIV resistance tests

Haplotype test: assessing the rate of HIV progression; genotype: drug resistance+correct therapy; HLA-B5701 don't use Abacavir drug

Unlock this slideshow and over 4 million more with Baamboozle+

Try slideshows