• UNIT 3
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  • What is the underlying pathogenesis of Von Gierk's (Type I) disease?
    glucose-6-phosphatase deficiency (can't go from G6P to Glucose)
  • Why does a person with a G6P deficiency need to eat corn starch?
    corn starch is a glucose polymer that is broken down slowly = control glucose levels
  • Why is there an increase in serum lactate acid in infants with Von Gierk's disease
    glucose-6-phosphate is also the substrate for glycolysis and produces lactate
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