Their names are Matt and Thomas.
Matt and Thomas are running. Matt and Thomas are not running. Are Matt and Thomas running? Are they running?
His name is Joe.
Joe is staying hydrated. Joe is not staying hydrated. Is Joe staying hydrated? Is he staying hydrated?
Their names are Brad and Patricia (the one sleeping is Peter... use Peter for the negative sentence)
Brad and Patricia are doing yoga. Peter is not doing yoga. Are Brad and Patricia doing yoga? Are they doing yoga?