Despite / In Spite Of
I don't like my job, I can't quit.
Despite the fact that I don't like my job, I can't quit. / In spite of the fact that...
Not having a breed, I love my dog.
Despite not having a breed, I love my dogl / In spite of not having a breed, I love my dog.
Middle / I can't travel. Having my passport.
I can't travel despite having my passport. / I can't travel in spite of having my passport.