Seek pt participation Help pt explore/compare treatments Asses pts values/preferences Reach decision together Evaluate pts w/ follow up

healthy adult, the serum CK level varies with a number of factors (gender, race and activity), but normal range is 22 to 198 U/L (units per liter)

Smoking Decreased physical activity Standard American Diet

Vitamin D deficiency is independently associated with myalgia, myositis, myopathy, myonecrosis; statins may affect vitamin D levels

Catechins may improve the lipid profile; reduction in total cholesterol; anti-inflammatory; stimulatory effects of caffeine

HDL LDL Triglycerides Total Cholesterol

Eat Better Move More Stress Less Love More

endogenous CoQ10 plays a role in muscle cell energy production; statins decrease endogenous CoQ10

reducing total cholesterol and LDL; increasing HDL; decrease coronary events and plaque; dosing should be titrated since it is lipid soluble; hyperglycemia/gout

decrease cholesterol protect against heart attack and stroke generally safe, highly effective

Coronary Artery Disease (CAD) Cerebral vascular disease Peripheral Vascular disease

During muscle degeneration, muscle cells break open and go into bloodstream. Rise in CK in the blood indicates that muscle damage occurred or is occurring

statin like properties; decrease obesity related inflammation, insulin resistance, nonalcoholic fatty liver disease; must be highly purified/certified